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DinI-like protein family : ウィキペディア英語版 | DinI-like protein family
In molecular biology, the DinI-like protein family is a family of short proteins. The family includes DNA-damage-inducible protein I (DinI) and related proteins. The SOS response, a set of cellular phenomena exhibited by eubacteria, is initiated by various causes that include DNA damage-induced replication arrest, and is positively regulated by the co-protease activity of RecA. ''Escherichia coli'' DinI, a LexA-regulated SOS gene product, shuts off the initiation of the SOS response when overexpressed ''in vivo''. Biochemical and genetic studies indicated that DinI physically interacts with RecA to inhibit its co-protease activity. The structure of DinI is known. ==References==
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